The disrupted molecular circadian clock of monocytes and macrophages in allergic inflammation

Abstract excerpt

Introduction Macrophage dysfunction is a common feature of inflammatory disorders such as asthma, which is characterized by a strong circadian rhythm. Methods and results We monitored the protein expression pattern of the molecular circadian clock in human peripheral blood monocytes from healthy, allergic, and asthmatic donors during a whole day. Monocytes cultured of these donors allowed us to examine circadian...

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• Share to Allergic Rhinitis and Sensitization
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