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Article

Dietary cholesterol interacts with SREBF1 to modulate obesity in Chinese children.

Molecular nutrition & food research - 1 Sept 2017

Zhang Shixiu, Lin Xinying, Lynn Henry, Xu Guifa, Li Jun, Zhao Changfeng, Li Mingmei

Abstract excerpt

SCOPE: Sterol regulatory element binding protein 1 gene (SREBF1) is an important candidate gene for obesity that could be affected by cholesterol. Different SREBF1 gene variants may have distinct responses to cholesterol, leading to different risks for obesity and obesity-related metabolic traits. Thus, we performed a gene-by-diet correlation analysis to test whether SREBF1 gene variation modulate the...

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PMID: 28333398
DOI: 10.1002/mnfr.201700105

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