Article
Polymorphisms in stearoyl coa desaturase and sterol regulatory element binding protein interact with N-3 polyunsaturated fatty acid intake to modify associations with anthropometric variables and metabolic phenotypes in Yup'ik people.
Molecular nutrition & food research - 1 Dec 2016
Lemas Dominick J, Klimentidis Yann C, Aslibekyan Stella, Wiener Howard W, O'Brien Diane M, Hopkins Scarlett E, Stanhope Kimber L, Havel Peter J, Allison David B, Fernandez Jose R, Tiwari Hemant K, Boyer Bert B
Abstract excerpt
SCOPE: n-3 polyunsaturated fatty acid (n-3 PUFA) intake is associated with protection from obesity; however, the mechanisms of protection remain poorly characterized. The stearoyl CoA desaturase (SCD), insulin-sensitive glucose transporter (SLC2A4), and sterol regulatory element binding protein (SREBF1) genes are transcriptionally regulated by n-3 PUFA intake and harbor polymorphisms associated with obesity. The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.