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Article

Tenofovir disoproxil fumarate-associated renal tubular dysfunction: noninvasive assessment of mitochondrial injury.

AIDS (London, England) - 1 Jun 2017

Samuels Ryan, Bayerri Carla Roca, Sayer John A, Price D Ashley, Payne Brendan A I

Abstract excerpt

OBJECTIVE: To determine whether tenofovir disoproxil fumarate (TDF)-associated renal tubular dysfunction is associated with evidence of mitochondrial injury in urine. DESIGN: Single-centre cross-sectional observational study of HIV-positive outpatients. METHODS: Biochemistry was performed on paired serum and urine samples. Mitochondrial DNA (mtDNA) was studied by real-time PCR and long-range PCR on cellular...

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Identifiers

PMID: 28323756
DOI: 10.1097/QAD.0000000000001466
PMCID: PMC5427982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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