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Decreased cortical FADD protein is associated with clinical dementia and cognitive decline in an elderly community sample

20 Mar 2017

Abstract excerpt

BACKGROUND: FADD (Fas-associated death domain) adaptor is a crucial protein involved in the induction of cell death but also mediates non-apoptotic actions via a phosphorylated form (p-Ser194-FADD). This study investigated the possible association of FADD forms with age-related neuropathologies, cognitive function, and the odds of dementia in an elderly community sample. METHODS: FADD forms were quantified by...

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Share to Alzheimer's disease research and treatments
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PMID: 28320441
DOI: 10.1186/s13024-017-0168-x

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