Article
Structural and functional studies of a noncanonical Dicer from Entamoeba histolytica.
Scientific reports - 20 Mar 2017
Yu Xiang, Li Xuhang, Zheng Lina, Ma Jinbiao, Gan Jianhua
Abstract excerpt
RNaseIII proteins are dsRNA-specific endonucleases involved in many important biological processes, such as small RNA processing and maturation in eukaryotes. Various small RNAs have been identified in a protozoan parasite Entamoeba histolytica. EhRNaseIII is the only RNaseIII endonuclease domain (RIIID)-containing protein in E. histolytica. Here, we present three crystal structures that reveal several unique...
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