Article
Intermediate states of ribonuclease III in complex with double-stranded RNA.
Structure (London, England : 1993) - 1 Oct 2005
Gan Jianhua, Tropea Joseph E, Austin Brian P, Court Donald L, Waugh David S, Ji Xinhua
Abstract excerpt
Bacterial ribonuclease III (RNase III) can affect RNA structure and gene expression in either of two ways: as a processing enzyme that cleaves double-stranded (ds) RNA, or as a binding protein that binds but does not cleave dsRNA. We previously proposed a model of the catalytic complex of RNase III with dsRNA based on three crystal structures, including the endonuclease domain of RNase III with and without bound...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.