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Article

Association of PTPRT Mutations with Cancer Metastasis in Multiple Cancer Types.

BioMed research international - 1 Jan 2022

Chen Chao, Liu Haozhen, Xu Qumiao, Zhang Xiuqing, Mu Feng, Liu Jixian

Abstract excerpt

Metastasis is one of the characteristics of advanced cancer and the primary cause of cancer-related deaths from cancer, but the mechanism underlying metastasis is unclear, and there is a lack of metastasis markers. PTPRT is a protein-coding gene involved in both signal transduction and cellular adhesion. It is also known as a tumor suppressor gene that inhibits cell malignant proliferation by inhibiting the STAT3...

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Source

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Identifiers

PMID: 35789644
DOI: 10.1155/2022/9386477
PMCID: PMC9250438

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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