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Article

HBV quasispecies composition in Lamivudine-failed chronic hepatitis B patients and its influence on virological response to Tenofovir-based rescue therapy.

Scientific reports - 17 Mar 2017

Banerjee Priyanka, Chakraborty Abhijit, Mondal Rajiv Kumar, Khatun Mousumi, Datta Somenath, Das Kausik, Pandit Pratap, Mukherjee Souvik, Banerjee Soma, Ghosh Saurabh, Chakrabarti Saikat, Chowdhury Abhijit, Datta Simanti

Abstract excerpt

The present study sought to evaluate the structure of HBV quasispecies in Lamivudine (LMV)-failed chronic hepatitis B (CHB) patients and its impact in defining the subsequent virological responses to Tenofovir (TDF)-based rescue-therapy. By analyzing HBV clones encompassing reverse transcriptase (RT) and surface (S) region from LMV-failed and treatment-naïve CHB patients, we identified 5 classical and 12 novel...

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Identifiers

PMID: 28303969
DOI: 10.1038/srep44742
PMCID: PMC5356183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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