Article
Effect of different γ-subunit isoforms on the regulation of AMPK.
The Biochemical journal - 9 May 2017
Willows Robin, Navaratnam Naveenan, Lima Ana, Read Jon, Carling David
Abstract excerpt
AMP-activated protein kinase (AMPK) plays a key role in integrating metabolic pathways in response to energy demand. AMPK activation results in a wide range of downstream responses, many of which are associated with improved metabolic outcome, making AMPK an attractive target for the treatment of metabolic diseases. AMPK is a heterotrimeric complex consisting of a catalytic subunit (α) and two regulatory subunits...
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