Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A repressive role of enhancer of zeste homolog 2 in 11β-hydroxysteroid dehydrogenase type 2 expression in the human placenta

1 Mar 2017

Abstract excerpt

The expression of 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2), which acts as a placental glucocorticoid barrier, is silenced in cytotrophoblasts but substantially up-regulated during syncytialization. However, the repressive mechanism of 11β-HSD2 expression before syncytialization and how this repression is lifted during syncytialization remain mostly unresolved. Here we found that enhancer of zeste...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Estrogen and related hormone effects
Share to Hormonal Regulation and Hypertension
Share to Sexual Differentiation and Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28302719
DOI: 10.1074/jbc.m116.765800

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A repressive role of enhancer of zeste homolog 2 in 11β-hydroxysteroid dehydrogenase type 2 expression in the human placentaPMID 28302719Read ↗

Critical Role of Histone Acetylation by p300 in Human Placental 11β-HSD2 ExpressionSemantic proximity Read ↗

Dynamic and distinct histone modifications facilitate human trophoblast lineage differentiationSemantic proximity Read ↗

The Attenuation of Trophoblast Invasion Caused by the Downregulation of EZH2 Is Involved in the Pathogenesis of Human Recurrent MiscarriageSemantic proximity Read ↗

SOX4 facilitates PGR protein stability and FOXO1 expression conducive for human endometrial decidualizationSemantic proximity Read ↗

Genome-wide analysis of histone modifications that underlie the dynamic changes in gene expression during decidualization in human endometrial stromal cellsSemantic proximity Read ↗

The cAMP-responsive element binding protein (CREB) transcription factor regulates furin expression during human trophoblast syncytializationSemantic proximity Read ↗

Histone deacetylase 1 and 2 drive differentiation and fusion of progenitor cells in human placental trophoblastsSemantic proximity Read ↗

H3K27me3-modulated Hofbauer cell BMP2 signalling enhancement compensates for shallow trophoblast invasion in preeclampsiaSemantic proximity Read ↗

Regulation of human trophoblast syncytialization by histone demethylase LSD1Semantic proximity Read ↗

Epigenetic regulation of the placental HSD11B2 barrier and its role as a critical regulator of fetal developmentSemantic proximity Read ↗

Estrogen-Related Receptor γ (ERRγ) Mediates Oxygen-Dependent Induction of Aromatase (CYP19) Gene Expression during Human Trophoblast DifferentiationSemantic proximity Read ↗

USF1 and USF2 Mediate Inhibition of Human Trophoblast Differentiation and CYP19 Gene Expression by Mash-2 and HypoxiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.