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Article

Topical simvastatin accelerates wound healing in diabetes by enhancing angiogenesis and lymphangiogenesis.

The American journal of pathology - 1 Dec 2012

Asai Jun, Takenaka Hideya, Hirakawa Satoshi, Sakabe Jun-ichi, Hagura Asami, Kishimoto Saburo, Maruyama Kazuichi, Kajiya Kentaro, Kinoshita Shigeru, Tokura Yoshiki, Katoh Norito

Abstract excerpt

Impaired wound healing is a major complication of diabetes. Recent studies have reported reduced lymphangiogenesis and angiogenesis during diabetic wound healing, which are thought to be new therapeutic targets. Statins have effects beyond cholesterol reduction and can stimulate angiogenesis when used systemically. However, the effects of topically applied statins on wound healing have not been well investigated....

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Source

Identifiers

PMID: 23138019
DOI: 10.1016/j.ajpath.2012.08.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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