Article
The effect of estrogen on diabetic wound healing is mediated through increasing the function of various bone marrow-derived progenitor cells.
Journal of vascular surgery - 1 Dec 2018
Zhuge Ying, Regueiro Manuela M, Tian Runxia, Li Yan, Xia Xiaomei, Vazquez-Padron Roberto, Elliot Sharon, Thaller Seth R, Liu Zhao-Jun, Velazquez Omaida C
Abstract excerpt
OBJECTIVE: Endothelial progenitor cells (EPCs) are the key cells of postnatal neovascularization, and mesenchymal stem cells (MSCs) possess pluripotent differentiation capacity and contribute to tissue regeneration and wound healing. Both EPCs and MSCs are critical to the wound repair process, which is hindered in diabetes mellitus. Diabetes has been shown to decrease the function of these progenitor cells,...
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