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Article

SFRP2 modulates functional phenotype transition and energy metabolism of macrophages during diabetic wound healing.

Frontiers in immunology - 1 Jan 2024

Yang Jiaqi, Xiong Guorui, He Huijuan, Huang Haili

Abstract excerpt

Diabetic foot ulcer (DFU) is a serious complication of diabetes mellitus, which causes great health damage and economic burden to patients. The pathogenesis of DFU is not fully understood. We screened wound healing-related genes using bioinformatics analysis, and full-thickness skin injury mice model and cellular assays were used to explore the role of target genes in diabetic wound healing. SFRP2 was identified...

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Share to Diabetes Mellitus, Experimental
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Energy Metabolism

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Share to Mice, Inbred C57BL

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Source

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Identifiers

PMID: 39464880
DOI: 10.3389/fimmu.2024.1432402
PMCID: PMC11502328

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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