Article
Programming of the Hypothalamus-Pituitary-Adrenal Axis by Very Preterm Birth.
Annals of nutrition & metabolism - 1 Jan 2017
Finken Martijn J J, van der Voorn Bibian, Hollanders Jonneke J, Ruys Charlotte A, de Waard Marita, van Goudoever Johannes B, Rotteveel Joost
Abstract excerpt
BACKGROUND: Many very preterm (i.e., <32 weeks of gestation) newborns fail to mount an adequate adrenocortical response to stress or illness, termed relative adrenal insufficiency. Conversely, later in life these infants show features of increased glucocorticoid bioactivity, such as abdominal adiposity, insulin resistance, raised blood pressure, shorter stature and internalizing problem behavior. SUMMARY: Studies...
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