Article
Protective effects of coffee against oxidative stress induced by the tobacco carcinogen benzo[α]pyrene.
Free radical biology & medicine - 1 Jul 2017
Kalthoff Sandra, Landerer Steffen, Reich Julia, Strassburg Christian P
Abstract excerpt
AIMS: Coffee consumption has been epidemiologically associated with a lower risk for liver cirrhosis and cancer. UDP-glucuronosyltransferases (UGT1A) catalyze the detoxification of reactive metabolites thereby acting as indirect antioxidants. Aim of the study was to examine UGT1A regulation in response to Benzo[α]pyrene (BaP) to elucidate the potentially protective effects of coffee on BaP-induced oxidative...
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