Article
Single nucleotide polymorphisms associated with nonsyndromic cryptorchidism in Mexican patients.
Andrologia - 1 Feb 2018
Chávez-Saldaña M, Vigueras-Villaseñor R M, Yokoyama-Rebollar E, Landero-Huerta D A, Rojas-Castañeda J C, Taja-Chayeb L, Cuevas-Alpuche J O, Zambrano E
Abstract excerpt
Cryptorchidism is a frequent genitourinary malformation considered as an important risk factor for infertility and testicular malignancy. The aetiology of cryptorchidism is multifactorial in which certain SNPs, capable of inhibiting the development of the gubernaculum, are implicated. We analysed 16 SNPs by allelic discrimination and automated sequencing in 85 patients and 99 healthy people, with the objective to...
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