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Article

Genetic Association of RXFP2 T222P Variant With Cryptorchidism: A Meta-Analytic Study.

Andrology - 1 Oct 2026

Kabziński Jacek, Niedzielski Jerzy, Majsterek Ireneusz

Abstract excerpt

BACKGROUND: The RXFP2 receptor plays a key role in testicular descent, mediating the action of relaxin on gubernaculum development. The T222P polymorphism in the RXFP2 gene has previously been investigated in relation to cryptorchidism, but reported associations have been inconsistent across populations. OBJECTIVES: The aim of this meta-analysis was to assess the association of the T222P variant in the RXFP2 gene...

Read the complete abstract on PubMed

Topics

Cryptorchidism
Humans
Male
Receptors, G-Protein-Coupled
Genetic Predisposition to Disease
Gene Frequency
Genetic Association Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genotype

Source

Identifiers

PMID: 41630538
DOI: 10.1111/andr.70187

Genes

RXFP2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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