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Article

Mega-scale Bayesian regression methods for genome-wide prediction and association studies with thousands of traits.

Genetics - 2 Mar 2023

Qu Jiayi, Runcie Daniel, Cheng Hao

Abstract excerpt

Large-scale phenotype data are expected to increase the accuracy of genome-wide prediction and the power of genome-wide association analyses. However, genomic analyses of high-dimensional, highly correlated traits are challenging. We developed a method for implementing high-dimensional Bayesian multivariate regression to simultaneously analyze genetic variants underlying thousands of traits. As a demonstration,...

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Identifiers

PMID: 36529897
DOI: 10.1093/genetics/iyac183
PMCID: PMC9991502

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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