Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Electrocardiogram changes and atrial arrhythmias in individuals carrying sodium channel SCN5A D1275N mutation.

Annals of medicine - 1 Sept 2017

Vanninen Sari U M, Nikus Kjell, Aalto-Setälä Katriina

Abstract excerpt

INTRODUCTION: The cardiac sodium channel SCN5A regulates atrioventricular and ventricular depolarization as well as cardiac conduction. Patients with cardiac electrical abnormalities have an increased risk of sudden cardiac death (SCD) and cardio-embolic stroke. Optimal management of cardiac disease includes the understanding of association between the causative mutations and the clinical phenotype. A 12-lead...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arrhythmias, Cardiac
Share to Electrocardiography
Share to Finland

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Atria

Share to Heart Conduction System

Share to NAV1.5 Voltage-Gated Sodium Channel

Share to Pedigree

Share to Young Adult

Source

Identifiers

PMID: 28294644
DOI: 10.1080/07853890.2017.1307515

Genes

SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Electrocardiogram changes and atrial arrhythmias in individuals carrying sodium channel SCN5A D1275N mutation.PMID 28294644Read ↗

SCN5A mutation associated with cardiac conduction defect and atrial arrhythmias.Semantic proximity Read ↗

SCN5A Variants: Association With Cardiac DisordersSemantic proximity Read ↗

Cardiac Arrhythmias Related to Sodium Channel Dysfunction.Semantic proximity Read ↗

Disease Modifiers of Inherited SCN5A ChannelopathySemantic proximity Read ↗

Clinical characterization of the first Belgian SCN5A founder mutation cohort.Semantic proximity Read ↗

Cardiac sodium channelopathy associated with SCN5A mutations: electrophysiological, molecular and genetic aspects.Semantic proximity Read ↗

Ventricular conduction is a marker for arrhythmic risk in SCN5A-E1784K overlap sodium channel disease.Semantic proximity Read ↗

A Novel SCN5A Variant Associated with Abnormal Repolarization, Atrial Fibrillation, and Reversible Cardiomyopathy.Semantic proximity Read ↗

Cardiac voltage-gated sodium channel mutations associated with left atrial dysfunction and stroke in children.Semantic proximity Read ↗

The cardiac sodium channel gene SCN5A and its gene product NaV1.5: Role in physiology and pathophysiology.Semantic proximity Read ↗

Analysis of Phenotypic and Genetic Characteristics of 37 Children with SCN5A Variants: from A Single Tertiary Medical Center in ChinaSemantic proximity Read ↗

Inherited cardiac diseases caused by mutations in the Nav1.5 sodium channel.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.