Article
The role of genetic susceptibility in the association of low birth weight with type 2 diabetes.
British medical bulletin - 1 Jan 2001
Frayling T M, Hattersley A T
Abstract excerpt
We suggest that altered fetal growth and type 2 diabetes may be two phenotypes of the same genotype - in other words the 'thrifty phenotype' is the result of a 'thrifty genotype'. Supporting this there is strong evidence that paternal factors and, therefore, genes influence fetal growth and that these paternal genes affecting fetal growth may also alter diabetes risk. Further study is needed to determine whether...
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