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Article

Generation and characterization of protective antibodies to Marburg virus

13 Mar 2017

Abstract excerpt

Marburg virus (MARV) and Ebola virus (EBOV) have been a source of epidemics and outbreaks for several decades. We present here the generation and characterization of the first protective antibodies specific for wild-type MARV. Non-human primates (NHP), cynomolgus macaques, were immunized with viral-replicon particles expressing the glycoproteins (GP) of MARV (Ci67 isolate). An antibody fragment (single-chain...

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PMID: 28287337
DOI: 10.1080/19420862.2017.1299848

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