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Generation of recombinant mAbs to vaccinia virus displaying high affinity and potent neutralization

22 Sept 2023

Abstract excerpt

ABSTRACT Members of the Orthopoxvirus genus can cause severe infections in humans. Global vaccination against smallpox, caused by the variola virus, resulted in the eradication of the disease in 1980. Shortly thereafter, vaccination was discontinued, and as a result, a large proportion of the current population is not protected against orthopoxviruses. The concerns that the variola virus or other engineered forms...

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PMID: 37737634
DOI: 10.1128/spectrum.01598-23

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