Article
miR-181d/MALT1 regulatory axis attenuates mesenchymal phenotype through NF-κB pathways in glioblastoma.
Cancer letters - 28 Jun 2017
Yang Fan, Liu Xing, Liu Yanwei, Liu Yuqing, Zhang Chuanbao, Wang Zheng, Jiang Tao, Wang Yongzhi
Abstract excerpt
The mesenchymal (MES) subtype of glioblastoma (GBM) indicated a more malignant phenotype and worse prognosis compared with their proneural (PN) counterpart. The plasticity between PN and MES transcriptome signatures provided an approach for clinical intervention. However, few miRNAs have been identified to participate in the shift between subtypes. Here, we utilized transcriptomic data and experimental evidences...
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