Article
Interferon-I: The Pièce de Résistance of HIV-1 Transmission?
Trends in microbiology - 1 May 2017
Tully Damien C, Claiborne Daniel T, Allen Todd M
Abstract excerpt
Despite the extensive viral quasispecies that develops in an individual during the course of HIV-1 infection, transmission is typically established by a single donor viral variant. Recent studies now provide insight into the phenotypic properties influencing this selection process at transmission, including the contribution of resistance to type I interferons.
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