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Article

Differences in the symptomatic phase preceding ACPA-positive and ACPA-negative RA: a longitudinal study in arthralgia during progression to clinical arthritis.

Annals of the rheumatic diseases - 1 Oct 2017

Burgers Leonie E, van Steenbergen Hanna W, Ten Brinck Robin M, Huizinga Tom Wj, van der Helm-van Mil Annette Hm

Abstract excerpt

OBJECTIVE: Although anticitrullinated protein antibody (ACPA)-positive and ACPA-negative rheumatoid arthritis (RA) have different aetiopathology, the clinical presentation at the time of diagnosis is similar. This study evaluated whether there are phenotypic differences in the symptomatic pre-RA phase. METHODS: Patients with arthralgia included in the Leiden clinically suspect arthralgia cohort who developed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28606964
DOI: 10.1136/annrheumdis-2017-211325

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