Article
The Genetic, Environmental, and Immunopathological Complexity of Autoantibody-Negative Rheumatoid Arthritis.
International journal of molecular sciences - 17 Nov 2021
De Stefano Ludovico, D'Onofrio Bernardo, Manzo Antonio, Montecucco Carlomaurizio, Bugatti Serena
Abstract excerpt
Differences in clinical presentation, response to treatment, and long-term outcomes between autoantibody-positive and -negative rheumatoid arthritis (RA) highlight the need for a better comprehension of the immunopathogenic events underlying the two disease subtypes. Whilst the drivers and perpetuators of autoimmunity in autoantibody-positive RA have started to be disclosed, autoantibody-negative RA remains...
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