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Article

Adjuvant treatment in early-stage endometrial cancer: context-dependent impact of somatic CTNNB1 mutation on recurrence-free survival.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 4 Jul 2022

Kurnit Katherine C, Fellman Bryan M, Mills Gordon B, Bowser Jessica L, Xie SuSu, Broaddus Russell R

Abstract excerpt

OBJECTIVE: The primary objective of this study was to determine whether women whose tumors harbor a somatic CTNNB1 mutation have longer recurrence-free survival if they receive traditional adjuvant therapy strategies compared with those who do not. METHODS: A retrospective, stage I endometrial cancer cohort from MD Anderson Cancer Center was assessed. Clinical and pathological characteristics and type of adjuvant...

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Identifiers

PMID: 35483739
DOI: 10.1136/ijgc-2021-003340
PMCID: PMC10811601

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