Article
Abnormal p53 expression is associated with poor outcomes in grade I or II, stage I, endometrioid carcinoma: a retrospective single-institute study.
Journal of gynecologic oncology - 1 Nov 2024
Chang Yu-Wei, Kuo Hsiao-Li, Chen Tzu-Chien, Chen Jessica, Lim Ling, Wang Kung-Liahng, Chen Jen-Ruei
Abstract excerpt
OBJECTIVE: The Cancer Genome Atlas study revealed an association between copy-number high (p53 abnormal) genetic mutation and poor prognosis in endometrial cancer in 2013. This retrospective study investigated outcomes in patients with abnormal p53 expression and stage I, low-grade endometrial endometrioid carcinoma (EEC). METHODS: We enrolled women with stage I, grade 1 or 2 EEC who received comprehensive...
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