Article
Analysis of CCR5 gene polymorphisms in 321 healthy Saudis using Next Generation Sequencing.
Human immunology - 1 Apr 2017
Al Balwi Mohammed A, Hadadi Ali I, Alharbi Wardah, Ballow Mariam, AlAsiri Abdulrahman, AlAbdulrahman Abdulkareem, G K Udayaraja, Aldrees Mohammed, AlAbdulkareem Ibrahim, Hajeer Ali H
Abstract excerpt
AIMS: To investigate the extent of CCR5 polymorphism in the healthy Saudi population. METHOD: A total of 321 healthy Saudi individuals were sequenced using the ion Ampliseq™ Exome kit (Life Technologies, USA) on genomic DNA following manufacturer's protocol. Whole Exome Sequencing (WES) reads were aligned to the human reference genome (hg19 build) with Torrent Suite Software (v5.0.2) and the variants were called...
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