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Article

Kaempferol Modulates DNA Methylation and Downregulates DNMT3B in Bladder Cancer

1 Jan 2017

Abstract excerpt

BACKGROUND: Genomic DNA methylation plays an important role in both the occurrence and development of bladder cancer. Kaempferol (Kae), a natural flavonoid that is present in many fruits and vegetables, exhibits potent anti-cancer effects in bladder cancer. Similar to other flavonoids, Kae possesses a flavan nucleus in its structure. This structure was reported to inhibit DNA methylation by suppressing DNA...

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PMID: 28278502
DOI: 10.1159/000464435

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