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Article

DNA Methylation Aberrations in Dimethylarsinic Acid-Induced Bladder Carcinogenesis

3 Nov 2023

Abstract excerpt

Arsenic is a known human urinary bladder carcinogen. While arsenic is known to cause aberrant DNA methylation, the mechanism of arsenic-triggered bladder carcinogenesis is not fully understood. The goal of this study was to identify aberrant DNA methylation in rat bladder urothelial carcinoma (UC) induced by dimethylarsinic acid (DMAV), a major organic metabolite of arsenic. We performed genome-wide DNA...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 37958445
DOI: 10.3390/cancers15215274

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