Flavonoids Influence Epigenetic-Modifying Enzyme Activity: Structure-Function Relationships and the Therapeutic Potential for Cancer

Abstract excerpt

Epigenetic modifications result in heritable changes in gene expression without changes to the DNA sequence. The most common forms of epigenetic regulation of gene expression are DNA methylation and histone acetylation or methylation, all of which are associated with chromatin remodeling. Results from recent studies suggest that epigenetic changes are some of the primary contributory factors of tumor-suppressor...

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