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Article

PTEN polymorphisms contribute to clinical outcomes of advanced lung adenocarcinoma patients treated with platinum-based chemotherapy.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2016

Yang Yang, Xu Wen, Liu Di, Ding Xi, Su Bo, Sun Yifeng, Gao Wen

Abstract excerpt

This study aimed to elucidate the impact of PTEN single nucleotide polymorphism (SNP) on clinical outcomes for advanced lung adenocarcinoma (LAC) patients treated with platinum-based chemotherapy. Three functional SNPs (rs11202607 G>A, rs701848 A>G, and rs11202592 G>C) of PTEN gene were genotyped by using DNA from blood samples of 618 advanced LAC patients, and their relationships with clinical outcomes were...

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Source

Identifiers

PMID: 26695147
DOI: 10.1007/s13277-015-4651-0

Genes

PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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