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Article

A translational approach to clinical practice via stress-responsive glucocorticoid receptor signaling

16 Feb 2017

Abstract excerpt

A recent article by Kwan and colleagues could elegantly demonstrate the necessary interaction between neuronal serotonin (5-HT) systems and the hypothalamic-pituitary-adrenal (HPA) axis through glucocorticoid receptors (GR), producing an adequate stress response, in this case, responding to hypoxia with an increase in hematopoietic stem and progenitor cells (HSPC). There is an intricate system connecting brain,...

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PMID: 28275643
DOI: 10.21037/sci.2017.02.01

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