Article
Methylene Tetrahydrofolate Reductase Gene Polymorphism is Associated with Severity of Liver Steatosis in Chronically Infected Patients with HCV Genotype 4.
Clinical laboratory - 1 Mar 2017
Dawood Reham M, Mahmoud Eman M, Ibrahim Marwa K, Din Noha G Bader El, Aboul-Enein Ahmed, Zayed Naglaa, Abd Yasmine S El, Eldeen Hadeel G, Eletreby Rasha, Elsharkawy Marwa, Omran Moataza, El-Shenawy Reem, Fayed Sayed A, Awady Mostafa K El
Abstract excerpt
BACKGROUND: Methylene tetrahydrofolate reductase (MTHFR) C677T polymorphism was reported as a genetic variant in liver steatosis and fibrosis. This is a study of the association between MTHFR C677T polymorphism and HCV core with severity of steatosis in HCV GT4 patients. METHODS: 111 HCV patients and 112 control subjects were recruited. Polymorphism was detected by RFLP analysis, core Ag was detected by ELISA....
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