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Methylenetetrahydrofolate reductase C677T polymorphism and liver fibrosis progression in patients with recurrent hepatitis C.

Liver international : official journal of the International Association for the Study of the Liver - 1 Feb 2008

Toniutto Pierluigi, Fabris Carlo, Falleti Edmondo, Cussigh Annarosa, Fontanini Elisabetta, Bitetto Davide, Fornasiere Ezio, Minisini Rosalba, De Feo Tullia, Marangoni Francesca, Pirisi Mario

Abstract excerpt

BACKGROUND/AIMS: Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism, being a putative steatogenic factor, may promote liver fibrosis progression in patients with chronic hepatitis C. This study aimed to verify the role of recipient MTHFR polymorphism in favouring graft fibrosis progression in patients with recurrent HCV after orthotopic liver transplantation (OLT). METHODS: We studied 63 such...

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Source

Identifiers

PMID: 17900242
DOI: 10.1111/j.1478-3231.2007.01591.x

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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