Article
DCL2- and RDR6-dependent transitive silencing of SMXL4 and SMXL5 in Arabidopsis dcl4 mutants causes defective phloem transport and carbohydrate over-accumulation.
The Plant journal : for cell and molecular biology - 1 Jun 2017
Wu Yu-Yi, Hou Bo-Han, Lee Wen-Chi, Lu Shin-Hua, Yang Chen-Jui, Vaucheret Hervé, Chen Ho-Ming
Abstract excerpt
DICER-LIKE (DCL) enzymes process double-stranded RNA into small RNAs that act as regulators of gene expression. Arabidopsis DCL4 and DCL2 each allow the post-transcriptional gene silencing (PTGS) of viruses and transgenes, but primary PTGS-prone DCL4 outcompetes transitive PTGS-prone DCL2 in wild-type plants. This hierarchy likely prevents DCL2 having any detrimental effects on endogenous genes. Indeed, dcl4...
Topics
- Arabidopsis
- Arabidopsis Proteins
- Carbohydrate Metabolism
- Cell Cycle Proteins
- Mutation
- Phloem
- Plants, Genetically Modified
- RNA-Dependent RNA Polymerase
- Ribonuclease III