Article
Hierarchical action and inhibition of plant Dicer-like proteins in antiviral defense.
Science (New York, N.Y.) - 7 Jul 2006
Deleris Angélique, Gallego-Bartolome Javier, Bao Jinsong, Kasschau Kristin D, Carrington James C, Voinnet Olivier
Abstract excerpt
The mechanisms underlying induction and suppression of RNA silencing in the ongoing plant-virus arms race are poorly understood. We show here that virus-derived small RNAs produced by Arabidopsis Dicer-like 4 (DCL4) program an effector complex conferring antiviral immunity. Inhibition of DCL4 by...
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