Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reconstitution of Saccharomyces cerevisiae DNA polymerase ε-dependent mismatch repair with purified proteins

6 Mar 2017

Abstract excerpt

Significance By performing reconstitution studies with purified Saccharomyces cerevisiae proteins, this study provides the first demonstration of eukaryotic mismatch repair (MMR) reactions dependent on DNA polymerase ε (Pol ε) in addition to the previously described DNA Pol δ (Pol δ)-dependent MMR reactions. The MutS homolog 2 (Msh2)–MutS homolog (or Msh2–MutS homolog 3)-dependent MMR reactions that Pol ε was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to DNA Repair Mechanisms
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28265089
DOI: 10.1073/pnas.1701753114

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reconstitution of Saccharomyces cerevisiae DNA polymerase ε-dependent mismatch repair with purified proteinsPMID 28265089Read ↗

Reconstitution of long and short patch mismatch repair reactions using <i>Saccharomyces cerevisiae</i> proteinsSemantic proximity Read ↗

Activation of Saccharomyces cerevisiae Mlh1-Pms1 Endonuclease in a Reconstituted Mismatch Repair System.Semantic proximity Read ↗

Rad27 and Exo1 function in different excision pathways for mismatch repair in Saccharomyces cerevisiae.Semantic proximity Read ↗

Reconstitution of 5′-Directed Human Mismatch Repair in a Purified SystemSemantic proximity Read ↗

Intrinsically disordered regions regulate both catalytic and non-catalytic activities of the MutLα mismatch repair complex.Semantic proximity Read ↗

Partial Reconstitution of Human DNA Mismatch Repair In Vitro: Characterization of the Role of Human Replication Protein ASemantic proximity Read ↗

Analysis of yeast pms1, msh2, and mlh1 mutators points to differences in mismatch correction efficiencies between prokaryotic and eukaryotic cells.Semantic proximity Read ↗

CAF-I-dependent control of degradation of the discontinuous strands during mismatch repairSemantic proximity Read ↗

Ligation of newly replicated DNA controls the timing of DNA mismatch repairSemantic proximity Read ↗

Biochemical reconstitution of temozolomide-induced mutational processes.Semantic proximity Read ↗

The multiple biological roles of the 3'-->5' exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domains.Semantic proximity Read ↗

MLH1, PMS1, and MSH2 Interactions During the Initiation of DNA Mismatch Repair in YeastSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.