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Article

Zhx2 (zinc fingers and homeoboxes 2) regulates major urinary protein gene expression in the mouse liver.

The Journal of biological chemistry - 21 Apr 2017

Jiang Jieyun, Creasy Kate Townsend, Purnell Justin, Peterson Martha L, Spear Brett T

Abstract excerpt

The mouse major urinary proteins (Mups) are encoded by a large family of highly related genes clustered on chromosome 4. Mups, synthesized primarily and abundantly in the liver and secreted through the kidneys, exhibit male-biased expression. Mups bind a variety of volatile ligands; these ligands, and Mup proteins themselves, influence numerous behavioral traits. Although urinary Mup protein levels vary between...

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Identifiers

PMID: 28258223
DOI: 10.1074/jbc.M116.768275
PMCID: PMC5399123

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