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Article

Model based heritability scores for high-throughput sequencing data.

BMC bioinformatics - 2 Mar 2017

Rudra Pratyaydipta, Shi W Jenny, Vestal Brian, Russell Pamela H, Odell Aaron, Dowell Robin D, Radcliffe Richard A, Saba Laura M, Kechris Katerina

Abstract excerpt

BACKGROUND: Heritability of a phenotypic or molecular trait measures the proportion of variance that is attributable to genotypic variance. It is an important concept in breeding and genetics. Few methods are available for calculating heritability for traits derived from high-throughput sequencing. RESULTS: We propose several statistical models and different methods to compute and test a heritability measure for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28253840
DOI: 10.1186/s12859-017-1539-6
PMCID: PMC5333443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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