Article
Chromosomal abnormalities and molecular landscape of metastasizing mucinous salivary adenocarcinoma.
Oral oncology - 1 Mar 2017
Panaccione Alex, Zhang Yi, Mi Yanfang, Mitani Yoshitsugu, Yan Guo, Prasad Manju L, McDonald W Hayes, El-Naggar Adel K, Yarbrough Wendell G, Ivanov Sergey V
Abstract excerpt
BACKGROUND: Mucinous adenocarcinoma of the salivary gland (MAC) is a lethal cancer with unknown molecular etiology and a high propensity to lymph node metastasis. Mostly due to its orphan status, MAC remains one of the least explored cancers that lacks cell lines and mouse models that could help translational and pre-clinical studies. Surgery with or without radiation remains the only treatment modality but poor...
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