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Article

Identification of somatic mutations using whole-exome sequencing in Korean patients with acute myeloid leukemia.

BMC medical genetics - 1 Mar 2017

Heo Seong Gu, Koh Youngil, Kim Jong Kwang, Jung Jongsun, Kim Hyung-Lae, Yoon Sung-Soo, Park Ji Wan

Abstract excerpt

BACKGROUND: Acute myeloid leukemia (AML) is a biologically and clinically heterogeneous cancer of the bone marrow that is characterized by the rapid growth of abnormal myeloid cells. METHODS: We performed a mutational analysis to identify AML somatic mutations using the whole-exome sequencing data of 36 tumor-normal sample pairs from Korean patients with de novo AML. We explored the functional impact of the genes...

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Identifiers

PMID: 28249600
DOI: 10.1186/s12881-017-0382-y
PMCID: PMC5333433

Genes

ATXN3
NEFH
TMPRSS13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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