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Article

Role of α/β interface in F1 ATPase rotational catalysis probed by inhibitors and mutations.

International journal of biological macromolecules - 1 Jun 2017

Sekiya Mizuki, Sakamoto Yasumitsu, Futai Masamitsu, Nakanishi-Matsui Mayumi

Abstract excerpt

The F1 sector of ATP synthase (FOF1) synthesizes or hydrolyses ATP via a rotational catalysis mechanism that couples chemical reaction with subunit rotation. Phytopolyphenols such as curcumin can inhibit bulk phase F1 ATPase activity by extending the catalytic dwell time during subunit rotation (Sekiya, M., Hisasaka, R., Iwamoto-Kihara, A., Futai, M., Nakanishi-Matsui, M., Biochem. Biophys. Res. Commun. 452...

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PMID: 28246051
DOI: 10.1016/j.ijbiomac.2017.02.089

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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