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Article

A rotor-stator cross-link in the F1-ATPase blocks the rate-limiting step of rotational catalysis.

The Journal of biological chemistry - 19 Sept 2008

Scanlon Joanne A Baylis, Al-Shawi Marwan K, Nakamoto Robert K

Abstract excerpt

The F(0)F(1)-ATP synthase couples the functions of H(+) transport and ATP synthesis/hydrolysis through the efficient transmission of energy mediated by rotation of the centrally located gamma, epsilon, and c subunits. To understand the gamma subunit role in the catalytic mechanism, we previously determined the partial rate constants and devised a minimal kinetic model for the rotational hydrolytic mode of the...

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Identifiers

PMID: 18628203
DOI: 10.1074/jbc.M804858200
PMCID: PMC2533770

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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A rotor-stator cross-link in the F1-ATPase blocks the rate-limiting step of rotational catalysis.PMID 18628203Read ↗

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