Article
Overlapping and segregating structural brain abnormalities in twins with schizophrenia or bipolar disorder.
Archives of general psychiatry - 1 Apr 2012
Hulshoff Pol Hilleke E, van Baal G Caroline M, Schnack Hugo G, Brans Rachel G H, van der Schot Astrid C, Brouwer Rachel M, van Haren Neeltje E M, Lepage Claude, Collins D Louis, Evans Alan C, Boomsma Dorret I, Nolen Willem, Kahn René S
Abstract excerpt
CONTEXT: The nosologic dichotomy between schizophrenia and bipolar disorder (BD) as formulated by Kraepelin is currently being questioned, stimulated by the finding that schizophrenia and BD partly share a common genetic origin. Although both disorders are characterized by changes in brain structure, family studies suggest more segregating than overlapping neuroanatomical abnormalities in both disorders....
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