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Article

Predicting network modules of cell cycle regulators using relative protein abundance statistics.

BMC systems biology - 28 Feb 2017

Oguz Cihan, Watson Layne T, Baumann William T, Tyson John J

Abstract excerpt

BACKGROUND: Parameter estimation in systems biology is typically done by enforcing experimental observations through an objective function as the parameter space of a model is explored by numerical simulations. Past studies have shown that one usually finds a set of "feasible" parameter vectors that fit the available experimental data equally well, and that these alternative vectors can make different predictions...

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PMID: 28241833
DOI: 10.1186/s12918-017-0409-1
PMCID: PMC5329933

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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