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Article

Identifying responsive modules by mathematical programming: an application to budding yeast cell cycle.

PloS one - 1 Jan 2012

Wen Zhenshu, Liu Zhi-Ping, Yan Yiqing, Piao Guanying, Liu Zhengrong, Wu Jiarui, Chen Luonan

Abstract excerpt

High-throughput biological data offer an unprecedented opportunity to fully characterize biological processes. However, how to extract meaningful biological information from these datasets is a significant challenge. Recently, pathway-based analysis has gained much progress in identifying biomarkers for some phenotypes. Nevertheless, these so-called pathway-based methods are mainly individual-gene-based or...

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PMID: 22848637
DOI: 10.1371/journal.pone.0041854
PMCID: PMC3405030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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