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Article

Expression of CD133 and CD44 in glioblastoma stem cells correlates with cell proliferation, phenotype stability and intra-tumor heterogeneity.

PloS one - 1 Jan 2017

Brown Daniel V, Filiz Gulay, Daniel Paul M, Hollande Frédéric, Dworkin Sebastian, Amiridis Stephanie, Kountouri Nicole, Ng Wayne, Morokoff Andrew P, Mantamadiotis Theo

Abstract excerpt

Glioblastoma (GBM) is a heterogeneous tumor of the brain with a poor prognosis due to recurrence and drug resistance following therapy. Genome-wide profiling has revealed the existence of distinct GBM molecular subtypes that respond differently to aggressive therapies. Despite this, molecular subtype does not predict recurrence or drug resistance and overall survival is similar across subtypes. One of the key...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28241049
DOI: 10.1371/journal.pone.0172791
PMCID: PMC5328356

Genes

GSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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